Acetaminophen

Evidence Level: N/A

Predicted Indications: 0

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Table of Contents

1. Acetaminophen
   1. Pharmacist Assessment Report
   2. Acetaminophen: Known uses and market status in Canada
   3. Summary
   4. Quick overview
   5. Known uses among the model’s candidates
      1. Approved (supported by a licence or label)
      2. Related to an approved indication (same disease category)
      3. Relations recorded in the knowledge graph (no approval found)
   6. Canada Market Information
   7. Safety Considerations
   8. Disclaimer

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Pharmacist Assessment Report

Acetaminophen: Known uses and market status in Canada

Summary

The TxGNN deep-learning model (score ≥ 0.99) produced candidate indications for Acetaminophen. Every candidate that can be traced to a source is already a known use. There is therefore currently no new predicted indication for this drug.

Quick overview

Item	Content
New predicted indications	None (all traceable model candidates are known uses)
Known uses among model candidates	0
Evidence level	Not applicable
Canada Market Status	Marketed (marketed DINs on record: at least 20)
Number of DINs	at least 20

Known uses among the model’s candidates

Approved (supported by a licence or label)

Indication	Source
none	none

Related to an approved indication (same disease category)

Indication	Approved category
none	none

Relations recorded in the knowledge graph (no approval found)

Indication
none

Canada Market Information

Licence	Product	Dosage form	Status
02230435	ACET 160		Valid
00482323	NOVO-GESIC FORTE		Valid
02022214	ACÉTAMINOPHÈNE COMPRIMÉ TABLET 325		Valid
02255251	ACETAMINOPHEN 500 MG TABLETS EXTRA STRENGTH EASY TO SWALLOW		Valid
02027801	PEDIATRIX DROPS		Valid
02447819	JUNIOR STRENGTH CHILDREN’S ACETAMINOPHEN TABLETS		Valid
02238885	TYLENOL ARTHRITIS PAIN 8H		Valid
01996169	ACETAMINOPHEN CHEWABLE TABLETS 160 MG		Valid
02017431	ACETAMINOPHEN CHEWABLE TABLETS 160 MG FOR CHILDREN		Valid
02285797	EXTRA STRENGTH ACETAMINOPHEN		Valid
02272482	ACETAMINOPHEN ARTHRITIS PAIN		Valid
02389908	INFANTS’ TYLENOL FEVER & SORE THROAT PAIN		Valid
02389924	CHILDREN’S TYLENOL FEVER & SORE THROAT PAIN		Valid
01977415	ACETAMINOPHEN CAPLETS 325 MG		Valid
02230437	ACET 650		Valid
02362341	ACETAMINOPHEN CAPLETS 325 MG		Valid
02548356	EXTRA STRENGTH EASY TABS 500 MG		Valid
02371146	ARTHRITIS PAIN RELIEF		Valid
02519631	ARTHRITIS PAIN RELIEF		Valid
00544981	APO-ACETAMINOPHEN		Valid

Only part of the licence list is held in the data; the list may be incomplete.

Safety Considerations

• Disease-related cautions (from the knowledge graph, not label text): liver failure, liver disease, cirrhosis of the liver, hepatic encephalopathy, hepatic coma and gallbladder disease.
• Drug Interactions: 100 interactions were found in total. The 20 shown in the data are mostly Minor.
  • Moderate: activated charcoal, glycerol phenylbutyrate, naltrexone.
  • Minor: mainly anticholinergic or antispasmodic agents (such as atropine, hyoscyamine, scopolamine, dicyclomine and glycopyrronium), H2 blockers (cimetidine, ranitidine), metoclopramide and liraglutide.
  • Unknown level: vitamin A and calcitriol.

Please refer to the package insert for the full warnings and contraindications.

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Disclaimer

This content is for research purposes only and does not constitute medical advice. Clinical validation is required before any clinical application.

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