Anakinra
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB00026 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | extracutaneous mastocytoma | KG + DL |
| 2 | hepatic infarction | KG + DL |
| 3 | autosomal recessive familial Mediterranean fever | KG + DL |
| 4 | aggressive systemic mastocytosis | KG + DL |
| 5 | hepatic veno-occlusive disease | KG + DL |
| 6 | peliosis hepatis | KG + DL |
| 7 | oligoarticular juvenile idiopathic arthritis without anti-nuclear antibodies | KG + DL |
| 8 | oligoarticular juvenile idiopathic arthritis with anti-nuclear antibodies | KG + DL |
| 9 | pyogenic autoinflammatory syndrome | KG + DL |
| 10 | unclassified autoinflammatory syndrome | KG + DL |
| 11 | granulomatous autoinflammatory syndrome | KG + DL |
| 12 | syndrome with combined immunodeficiency | KG + DL |
| 13 | liver angiosarcoma | KG + DL |
| 14 | mastocytosis | KG + DL |
| 15 | Kimura disease | KG + DL |
| 16 | indolent systemic mastocytosis | KG + DL |
| 17 | bilateral parasagittal parieto-occipital polymicrogyria | KG + DL |
| 18 | familial Mediterranean fever, autosomal dominant | KG + DL |
| 19 | hepatic veno-occlusive disease-immunodeficiency syndrome | KG + DL |
| 20 | amyotrophic lateral sclerosis | KG + DL |
| 21 | axial spondylometaphyseal dysplasia | KG + DL |
| 22 | lower motor neuron syndrome with late-adult onset | KG + DL |
| 23 | trichomegaly-retina pigmentary degeneration-dwarfism syndrome | KG + DL |
| 24 | amyotrophic lateral sclerosis, susceptibility to | KG + DL |
| 25 | Mills syndrome | KG + DL |
| 26 | amyotrohpic lateral sclerosis type 22 | KG + DL |
| 27 | X-linked lymphoproliferative disease due to SH2D1A deficiency | KG + DL |
| 28 | monomelic amyotrophy | KG + DL |
| 29 | lethal arthrogryposis-anterior horn cell disease syndrome | KG + DL |
| 30 | pancytopenia due to IKZF1 mutations | KG + DL |
| 31 | Budd-Chiari syndrome | KG + DL |
| 32 | autosomal dominant mitochondrial myopathy with exercise intolerance | KG + DL |
| 33 | combined immunodeficiency due to CRAC channel dysfunction | KG + DL |
| 34 | familial Mediterranean fever | KG + DL |
| 35 | dermatofibrosarcoma protuberans | KG + DL |
| 36 | hemophagocytic syndrome associated with an infection | KG + DL |
| 37 | acquired hemophagocytic lymphohistiocytosis associated with malignant disease | KG + DL |
| 38 | hidradenitis suppurativa | KG + DL |
| 39 | systemic-onset juvenile idiopathic arthritis | KG + DL |
| 40 | familial thrombocytosis | KG + DL |
| 41 | hepatic vein thrombosis | KG + DL |
| 42 | autoinflammatory syndrome with pyogenic bacterial infection and amylopectinosis | KG + DL |
| 43 | chromhidrosis | KG + DL |
| 44 | primary immunodeficiency due to a defect in adaptive immunity | KG + DL |
| 45 | facial dysmorphism-immunodeficiency-livedo-short stature syndrome | KG + DL |
| 46 | absent thumb-short stature-immunodeficiency syndrome | KG + DL |
| 47 | A20 haploinsufficiency | KG + DL |
| 48 | immuno-osseous dysplasia | KG + DL |
| 49 | immune dysregulation with inflammatory bowel disease | KG + DL |
| 50 | periodic fever-infantile enterocolitis-autoinflammatory syndrome | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.