Topiramate
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB00273 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 23 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | trigeminal nerve neoplasm | KG + DL |
| 2 | visual epilepsy | KG + DL |
| 3 | audiogenic seizures | KG + DL |
| 4 | eating seizures | KG + DL |
| 5 | startle epilepsy | KG + DL |
| 6 | micturation-induced seizures | KG + DL |
| 7 | thinking seizures | KG + DL |
| 8 | orgasm-induced seizures | KG + DL |
| 9 | reading seizures | KG + DL |
| 10 | trigeminal neuralgia | KG + DL |
| 11 | beta-ketothiolase deficiency | KG + DL |
| 12 | status epilepticus | KG + DL |
| 13 | Rett syndrome, congenital variant | KG + DL |
| 14 | 14q12 microdeletion syndrome | KG + DL |
| 15 | restless legs syndrome | KG + DL |
| 16 | partial motor epilepsy | KG + DL |
| 17 | adolescent/adult onset autosomal dominant epilepsy with auditory features | KG + DL |
| 18 | febrile infection-related epilepsy syndrome | KG + DL |
| 19 | photosensitive occipital lobe epilepsy | KG + DL |
| 20 | atypical childhood epilepsy with centrotemporal spikes | KG + DL |
| 21 | cryptogenic late-onset epileptic spasms | KG + DL |
| 22 | perioral myoclonia with absences | KG + DL |
| 23 | guanidinoacetate methyltransferase deficiency | KG + DL |
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.