Levothyroxine Sodium
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB00451 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | endemic goiter | KG + DL |
| 2 | renal hypodysplasia/aplasia | KG + DL |
| 3 | nodular goiter (disease) | KG + DL |
| 4 | bilateral renal agenesis | KG + DL |
| 5 | nontoxic goiter | KG + DL |
| 6 | substernal goiter | KG + DL |
| 7 | dyshormonogenic goiter | KG + DL |
| 8 | lingual goiter | KG + DL |
| 9 | Potter sequence | KG + DL |
| 10 | Carney complex | KG + DL |
| 11 | hypotrichosis simplex of the scalp | KG + DL |
| 12 | peripheral dysostosis | KG + DL |
| 13 | inflammatory linear verrucous epidermal nevus | KG + DL |
| 14 | acrodysostosis with or without hormone resistance | KG + DL |
| 15 | giant congenital nevus | KG + DL |
| 16 | 46,XY disorder of sex development due to testicular steroidogenesis defect | KG + DL |
| 17 | myxoma | KG + DL |
| 18 | angiomyxoma | KG + DL |
| 19 | papillary thyroid Microcarcinoma | KG + DL |
| 20 | thyroid carcinoma, nonmedullary, with or without cell oxyphilia | KG + DL |
| 21 | congenital hypotrichosis milia | KG + DL |
| 22 | melanocytic nevus | KG + DL |
| 23 | rectum adenocarcinoma | KG + DL |
| 24 | verrucous nevus syndrome | KG + DL |
| 25 | homozygous familial hypercholesterolemia | KG + DL |
| 26 | resistance to thyrotropin-releasing hormone syndrome | KG + DL |
| 27 | thyroid adenoma (disease) | KG + DL |
| 28 | longitudinal vaginal septum | KG + DL |
| 29 | transverse vaginal septum | KG + DL |
| 30 | epithelioid malignant peripheral nerve sheath tumor | KG + DL |
| 31 | hair nevus | KG + DL |
| 32 | vulvar inverted follicular keratosis | KG + DL |
| 33 | rectal carcinoma | KG + DL |
| 34 | double outlet right ventricle with atrioventricular septal defect, pulmonary stenosis, heterotaxy | KG + DL |
| 35 | atrophy of thyroid | KG + DL |
| 36 | cutaneous fibrous histiocytoma | KG + DL |
| 37 | isolated thyroid-stimulating hormone deficiency | KG + DL |
| 38 | rectal cancer | KG + DL |
| 39 | neurofibrosarcoma | KG + DL |
| 40 | diffuse alopecia areata | KG + DL |
| 41 | syringoma | KG + DL |
| 42 | hidradenoma | KG + DL |
| 43 | skin papilloma | KG + DL |
| 44 | hypothyroidism due to iodide transport defect | KG + DL |
| 45 | generalized resistance to thyroid hormone | KG + DL |
| 46 | skin tag | KG + DL |
| 47 | benign thyroid gland neoplasm | KG + DL |
| 48 | hypothyroidism, congenital, nongoitrous | KG + DL |
| 49 | primary hereditary glaucoma | KG + DL |
| 50 | peripheral resistance to thyroid hormones | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.