Irinotecan Hydrochloride
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB00762 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 65 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | female breast carcinoma | KG + DL |
| 2 | pancreatic carcinoma with mixed differentiation | KG + DL |
| 3 | solid pseudopapillary carcinoma of pancreas | KG + DL |
| 4 | osteoclastic giant cell tumor of pancreas | KG + DL |
| 5 | pancreatic intraductal papillary-mucinous carcinoma | KG + DL |
| 6 | pancreatic intraductal papillary-mucinous neoplasm | KG + DL |
| 7 | pancreatic signet ring cell adenocarcinoma | KG + DL |
| 8 | mixed ductal-endocrine carcinoma of pancreas | KG + DL |
| 9 | malignant exocrine pancreas neoplasm | KG + DL |
| 10 | undifferentiated pancreatic carcinoma | KG + DL |
| 11 | pancreatic serous cystadenocarcinoma | KG + DL |
| 12 | pancreatic acinar cell cystadenocarcinoma | KG + DL |
| 13 | pancreatic mucinous cystadenocarcinoma | KG + DL |
| 14 | botryoid-type embryonal rhabdomyosarcoma of the vagina | KG + DL |
| 15 | rhabdomyosarcoma (disease) | KG + DL |
| 16 | extrahepatic bile duct rhabdomyosarcoma | KG + DL |
| 17 | embryonal extrahepatic bile duct rhabdomyosarcoma | KG + DL |
| 18 | liver sarcoma | KG + DL |
| 19 | prostate embryonal rhabdomyosarcoma | KG + DL |
| 20 | parameningeal embryonal rhabdomyosarcoma | KG + DL |
| 21 | skeletal muscle neoplasm | KG + DL |
| 22 | colloid carcinoma of the pancreas | KG + DL |
| 23 | metastatic malignant neoplasm in the colon | KG + DL |
| 24 | metastatic carcinoma | KG + DL |
| 25 | metastatic malignant neoplasm in the spinal cord | KG + DL |
| 26 | T-lymphoblastic lymphoma | KG + DL |
| 27 | T-cell childhood lymphoblastic lymphoma | KG + DL |
| 28 | colon sarcoma | KG + DL |
| 29 | metastatic malignant neoplasm in the eye | KG + DL |
| 30 | malignant pleural mesothelioma | KG + DL |
| 31 | primary pulmonary lymphoma | KG + DL |
| 32 | pancreatic mucinous cystadenoma | KG + DL |
| 33 | synovial chondromatosis | KG + DL |
| 34 | orbit sarcoma | KG + DL |
| 35 | well-differentiated fetal adenocarcinoma of the lung | KG + DL |
| 36 | giant cell tumor of soft tissue | KG + DL |
| 37 | sarcoma, avian | KG + DL |
| 38 | transverse colon cancer | KG + DL |
| 39 | pulmonary blastoma | KG + DL |
| 40 | Ewing sarcoma | KG + DL |
| 41 | malignant epithelioid mesothelioma | KG + DL |
| 42 | uterine corpus sarcoma | KG + DL |
| 43 | small cell lung carcinoma | KG + DL |
| 44 | sarcomatoid mesothelioma | KG + DL |
| 45 | benign neoplasm of tongue | KG + DL |
| 46 | cervical neuroblastoma | KG + DL |
| 47 | benign neoplasm of floor of mouth | KG + DL |
| 48 | epiglottis neoplasm | KG + DL |
| 49 | nasopharyngeal teratoma | KG + DL |
| 50 | tumor of testis and paratestis | KG + DL |
(Showing top 50 of 65 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.