Alprostadil
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB00770 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 59 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | aortic malformation | KG + DL |
| 2 | congenital tricuspid stenosis | KG + DL |
| 3 | congenital valvular dysplasia | KG + DL |
| 4 | tricuspid valve agenesis | KG + DL |
| 5 | straddling or overriding tricuspid valve | KG + DL |
| 6 | tricuspid valve prolapse (disease) | KG + DL |
| 7 | anomaly of the tricuspid subvalvular apparatus | KG + DL |
| 8 | double outlet right ventricle with atrioventricular septal defect, pulmonary stenosis, heterotaxy | KG + DL |
| 9 | heart septal defect | KG + DL |
| 10 | endemic goiter | KG + DL |
| 11 | mitral atresia disorder | KG + DL |
| 12 | mehta lewis patton syndrome | KG + DL |
| 13 | congenital aortic valve insufficiency | KG + DL |
| 14 | subaortic stenosis | KG + DL |
| 15 | double outlet right ventricle with non-committed subpulmonary ventricular septal defect | KG + DL |
| 16 | congenital pulmonary venous return anomaly | KG + DL |
| 17 | amenorrhea (disease) | KG + DL |
| 18 | non-syndromic esophageal malformation | KG + DL |
| 19 | aortic valve stenosis | KG + DL |
| 20 | aortic arch interruption | KG + DL |
| 21 | double outlet right ventricle with subpulmonary ventricular septal defect | KG + DL |
| 22 | pulmonic stenosis (disease) | KG + DL |
| 23 | nodular goiter (disease) | KG + DL |
| 24 | patent ductus arteriosus | KG + DL |
| 25 | subaortic stenosis, membranous | KG + DL |
| 26 | familial bicuspid aortic valve | KG + DL |
| 27 | esotropia | KG + DL |
| 28 | pulmonary atresia-intact ventricular septum syndrome | KG + DL |
| 29 | genetic vascular tumor | KG + DL |
| 30 | transposition of the great arteries and conotruncal cardiac anomaly | KG + DL |
| 31 | arterial duct anomaly | KG + DL |
| 32 | conotruncal heart malformations | KG + DL |
| 33 | dextrocardia (disease) | KG + DL |
| 34 | partial atrioventricular canal | KG + DL |
| 35 | nontoxic goiter | KG + DL |
| 36 | substernal goiter | KG + DL |
| 37 | dyshormonogenic goiter | KG + DL |
| 38 | lingual goiter | KG + DL |
| 39 | atrial septal defect, ostium secundum type | KG + DL |
| 40 | persistent truncus arteriosus (disease) | KG + DL |
| 41 | double outlet right ventricle | KG + DL |
| 42 | double outlet right ventricle with subaortic or doubly committed ventricular septal defect | KG + DL |
| 43 | congenital non-communicating hydrocephalus | KG + DL |
| 44 | tricuspid valve disease | KG + DL |
| 45 | congenital anomaly of the great arteries | KG + DL |
| 46 | heart defects-limb shortening syndrome | KG + DL |
| 47 | Blake pouch cyst | KG + DL |
| 48 | patent foramen ovale (disease) | KG + DL |
| 49 | Axenfeld-Rieger syndrome | KG + DL |
| 50 | esophageal disease | KG + DL |
(Showing top 50 of 59 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.