Cysteamine
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB00847 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | mitochondrial oxidative phosphorylation disorder due to nuclear DNA anomalies | KG + DL |
| 2 | inborn disorder of lysosomal amino acid transport | KG + DL |
| 3 | ocular cystinosis | KG + DL |
| 4 | exocrine pancreatic insufficiency | KG + DL |
| 5 | free sialic acid storage disease | KG + DL |
| 6 | Hurler syndrome | KG + DL |
| 7 | Steel syndrome | KG + DL |
| 8 | Gaucher disease | KG + DL |
| 9 | autosomal ichthyosis syndrome with fatal disease course | KG + DL |
| 10 | glycogen storage disease due to GLUT2 deficiency | KG + DL |
| 11 | esophageal varices with bleeding | KG + DL |
| 12 | esophageal varices without bleeding | KG + DL |
| 13 | Scheie syndrome | KG + DL |
| 14 | hypophosphatasia | KG + DL |
| 15 | phosphoribosylpyrophosphate synthetase superactivity | KG + DL |
| 16 | lysosomal storage disease with skeletal involvement | KG + DL |
| 17 | familial apolipoprotein C-II deficiency | KG + DL |
| 18 | polycystic kidney disease 3 with or without polycystic liver disease | KG + DL |
| 19 | benign neoplasm of adrenal gland | KG + DL |
| 20 | renal-hepatic-pancreatic dysplasia | KG + DL |
| 21 | autosomal dominant keratitis | KG + DL |
| 22 | Joubert syndrome with renal defect | KG + DL |
| 23 | Gaucher disease perinatal lethal | KG + DL |
| 24 | varicose disease | KG + DL |
| 25 | karyomegalic interstitial nephritis | KG + DL |
| 26 | autosomal dominant Alport syndrome | KG + DL |
| 27 | proximal myopathy with extrapyramidal signs | KG + DL |
| 28 | thoracic malformation | KG + DL |
| 29 | primary bone dysplasia | KG + DL |
| 30 | polycystic kidney disease | KG + DL |
| 31 | encephalopathy due to prosaposin deficiency | KG + DL |
| 32 | lysosomal disease with hypertrophic cardiomyopathy | KG + DL |
| 33 | adult familial nephronophthisis-spastic quadriparesia syndrome | KG + DL |
| 34 | syndromic neurometabolic disease with X-linked intellectual disability | KG + DL |
| 35 | monilethrix | KG + DL |
| 36 | Krabbe disease | KG + DL |
| 37 | metachromatic leukodystrophy | KG + DL |
| 38 | congenital stationary night blindness autosomal dominant | KG + DL |
| 39 | skeletal muscle disease | KG + DL |
| 40 | familial restrictive cardiomyopathy | KG + DL |
| 41 | contractures, pterygia, and spondylocarpotarsal fusion syndrome 1A | KG + DL |
| 42 | cholesteryl ester storage disease | KG + DL |
| 43 | generalized basal epidermolysis bullosa simplex with skin atrophy, scarring and hair loss | KG + DL |
| 44 | autosomal dominant Ehlers-Danlos syndrome, vascular type | KG + DL |
| 45 | eyelids malposition disorder | KG + DL |
| 46 | Flynn-Aird syndrome | KG + DL |
| 47 | autosomal dominant spastic ataxia | KG + DL |
| 48 | autosomal dominant Kenny-Caffey syndrome | KG + DL |
| 49 | monosomy X | KG + DL |
| 50 | autosomal dominant pure spastic paraplegia | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.