Mitoxantrone
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB01204 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | upper aerodigestive tract neoplasm | KG + DL |
| 2 | small cell lung carcinoma | KG + DL |
| 3 | primary pulmonary lymphoma | KG + DL |
| 4 | well-differentiated fetal adenocarcinoma of the lung | KG + DL |
| 5 | pulmonary blastoma | KG + DL |
| 6 | chronic myelogenous leukemia, BCR-ABL1 positive | KG + DL |
| 7 | head and neck cancer | KG + DL |
| 8 | bladder exstrophy-epispadias-cloacal exstrophy complex | KG + DL |
| 9 | bulbar polio | KG + DL |
| 10 | adenosarcoma | KG + DL |
| 11 | bladder exstrophy (disease) | KG + DL |
| 12 | uterine ligament adenosarcoma | KG + DL |
| 13 | skull base chordoma | KG + DL |
| 14 | malignant neoplasm of acoustic nerve | KG + DL |
| 15 | paranasal sinus cancer | KG + DL |
| 16 | vestibule of mouth cancer | KG + DL |
| 17 | retromolar area cancer | KG + DL |
| 18 | 5q35 microduplication syndrome | KG + DL |
| 19 | malignant mixed epithelial and mesenchymal tumor of cervix uteri | KG + DL |
| 20 | soft palate cancer | KG + DL |
| 21 | uveal cancer | KG + DL |
| 22 | inner ear cancer | KG + DL |
| 23 | middle ear cancer | KG + DL |
| 24 | acute lymphoblastic/lymphocytic leukemia | KG + DL |
| 25 | external ear cancer | KG + DL |
| 26 | ganglioneuroblastoma (disease) | KG + DL |
| 27 | cornea cancer | KG + DL |
| 28 | vertebral anomalies and variable endocrine and T-cell dysfunction | KG + DL |
| 29 | retroperitoneal neoplasm | KG + DL |
| 30 | ALK-positive large B-cell lymphoma | KG + DL |
| 31 | osteopathia striata with cranial sclerosis | KG + DL |
| 32 | Ewing sarcoma | KG + DL |
| 33 | Keipert syndrome | KG + DL |
| 34 | neuroblastoma | KG + DL |
| 35 | chronic lymphocytic leukemia/small lymphocytic lymphoma with immunoglobulin heavy chain variable-region gene somatic hypermutation | KG + DL |
| 36 | pregerminal center chronic lymphocytic leukemia/small lymphocytic lymphoma | KG + DL |
| 37 | acute myeloid leukemia and myelodysplastic syndromes related to radiation | KG + DL |
| 38 | acute myeloid leukemia and myelodysplastic syndromes related to alkylating agent | KG + DL |
| 39 | split hand, unilateral | KG + DL |
| 40 | acute panmyelosis with myelofibrosis | KG + DL |
| 41 | neuralgic amyotrophy | KG + DL |
| 42 | obsolete Hodgkin’s granuloma | KG + DL |
| 43 | leukemia (disease) | KG + DL |
| 44 | limb-mammary syndrome | KG + DL |
| 45 | blast phase chronic myelogenous leukemia, BCR-ABL1 positive | KG + DL |
| 46 | myelodysplastic/myeloproliferative disease | KG + DL |
| 47 | lissencephaly spectrum disorders | KG + DL |
| 48 | breast papillomatosis | KG + DL |
| 49 | salivary gland type cancer of the breast | KG + DL |
| 50 | amyotrophic neuralgia | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.