Cobimetinib
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB05239 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 44 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | amyotrophic lateral sclerosis | KG + DL |
| 2 | bilateral parasagittal parieto-occipital polymicrogyria | KG + DL |
| 3 | axial spondylometaphyseal dysplasia | KG + DL |
| 4 | Mills syndrome | KG + DL |
| 5 | amyotrophic lateral sclerosis, susceptibility to | KG + DL |
| 6 | lower motor neuron syndrome with late-adult onset | KG + DL |
| 7 | trichomegaly-retina pigmentary degeneration-dwarfism syndrome | KG + DL |
| 8 | lethal arthrogryposis-anterior horn cell disease syndrome | KG + DL |
| 9 | amyotrohpic lateral sclerosis type 22 | KG + DL |
| 10 | monomelic amyotrophy | KG + DL |
| 11 | autosomal dominant mitochondrial myopathy with exercise intolerance | KG + DL |
| 12 | choroideremia | KG + DL |
| 13 | non-cutaneous melanoma | KG + DL |
| 14 | epithelioid cell melanoma | KG + DL |
| 15 | eyelid melanoma | KG + DL |
| 16 | scrotum melanoma | KG + DL |
| 17 | choroidal dystrophy, central areolar | KG + DL |
| 18 | superficial spreading melanoma | KG + DL |
| 19 | CDK4 linked melanoma | KG + DL |
| 20 | amelanotic skin melanoma | KG + DL |
| 21 | lentigo maligna melanoma | KG + DL |
| 22 | nodular malignant melanoma | KG + DL |
| 23 | malignant melanoma of the mucosa | KG + DL |
| 24 | acral lentiginous melanoma (disease) | KG + DL |
| 25 | balloon cell malignant melanoma | KG + DL |
| 26 | intestinal obstruction in the newborn due to guanylate cyclase 2C deficiency | KG + DL |
| 27 | poliomyelitis | KG + DL |
| 28 | breast papillomatosis | KG + DL |
| 29 | salivary gland type cancer of the breast | KG + DL |
| 30 | systemic mastocytosis | KG + DL |
| 31 | fibroepithelial neoplasm | KG + DL |
| 32 | diabetic mastopathy | KG + DL |
| 33 | benign neoplasm of male breast | KG + DL |
| 34 | giant adenofibroma of the breast | KG + DL |
| 35 | infiltrating nipple syringomatous adenoma | KG + DL |
| 36 | subareolar duct papillomatosis | KG + DL |
| 37 | Smouldering systemic mastocytosis | KG + DL |
| 38 | breast myoepitheliosis | KG + DL |
| 39 | breast lipoma | KG + DL |
| 40 | granular cell tumor | KG + DL |
| 41 | benign eccrine breast spiradenoma | KG + DL |
| 42 | intraductal breast papillomatosis | KG + DL |
| 43 | breast cyst | KG + DL |
| 44 | borderline ovarian serous tumor | KG + DL |
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.