Obeticholic Acid
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB05990 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | rheumatoid arthritis | KG + DL |
| 2 | conjunctivitis | KG + DL |
| 3 | colobomatous microphthalmia-rhizomelic dysplasia syndrome | KG + DL |
| 4 | brachydactyly-syndactyly syndrome | KG + DL |
| 5 | brain small vessel disease 1 with or without ocular anomalies | KG + DL |
| 6 | autosomal dominant familial hematuria-retinal arteriolar tortuosity-contractures syndrome | KG + DL |
| 7 | heart disease | KG + DL |
| 8 | orofacial clefting syndrome | KG + DL |
| 9 | Pierre Robin syndrome associated with a chromosomal anomaly | KG + DL |
| 10 | Jeune syndrome situs inversus | KG + DL |
| 11 | Prinzmetal angina | KG + DL |
| 12 | Laubry-Pezzi syndrome | KG + DL |
| 13 | interventricular septum aneurysm | KG + DL |
| 14 | genetic syndromic Pierre Robin syndrome | KG + DL |
| 15 | partial deletion of the long arm of chromosome 7 | KG + DL |
| 16 | pulmonary valve disease | KG + DL |
| 17 | disorder of fucoglycosan synthesis | KG + DL |
| 18 | thrombotic disease | KG + DL |
| 19 | partial deletion of the long arm of chromosome 22 | KG + DL |
| 20 | mitral valve disease | KG + DL |
| 21 | diabetic nephropathy | KG + DL |
| 22 | conjunctivitis (disease) | KG + DL |
| 23 | heart conduction disease | KG + DL |
| 24 | hyperthyroidism | KG + DL |
| 25 | sclerosing cholangitis | KG + DL |
| 26 | gout | KG + DL |
| 27 | acute contagious conjunctivitis | KG + DL |
| 28 | hemoglobinopathy | KG + DL |
| 29 | heart valve disease | KG + DL |
| 30 | myocardial disorder | KG + DL |
| 31 | resistance to thyroid hormone due to a mutation in thyroid hormone receptor beta | KG + DL |
| 32 | vein disease | KG + DL |
| 33 | heart neoplasm | KG + DL |
| 34 | autoimmune hemolytic anemia | KG + DL |
| 35 | congenital anomaly of ventricular septum | KG + DL |
| 36 | angiodysplasia | KG + DL |
| 37 | postoperative ventricular dysfunction | KG + DL |
| 38 | non-inflammatory vasculopathy | KG + DL |
| 39 | fibrocartilaginous embolism | KG + DL |
| 40 | venous thromboembolism | KG + DL |
| 41 | pericardium disease | KG + DL |
| 42 | partial deletion of the short arm of chromosome 16 | KG + DL |
| 43 | beta-thalassemia with other manifestations | KG + DL |
| 44 | patent ductus arteriosus-bicuspid aortic valve-hand anomalies syndrome | KG + DL |
| 45 | hemolytic anemia due to glucophosphate isomerase deficiency | KG + DL |
| 46 | bronchitis | KG + DL |
| 47 | leprosy | KG + DL |
| 48 | tendinitis | KG + DL |
| 49 | acquired aplastic anemia | KG + DL |
| 50 | respiratory tract infectious disease | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.