Bosutinib
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB06616 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | myeloid leukemia | KG + DL |
| 2 | thrombocytopenia | KG + DL |
| 3 | marcothrombocytopenia with mitral valve insufficiency | KG + DL |
| 4 | hereditary thrombocytopenia with normal platelets | KG + DL |
| 5 | transient neonatal thrombocytopenia | KG + DL |
| 6 | dense granule disease | KG + DL |
| 7 | platelet storage pool deficiency | KG + DL |
| 8 | plasma cell myeloma | KG + DL |
| 9 | HER2 positive breast carcinoma | KG + DL |
| 10 | indolent plasma cell myeloma | KG + DL |
| 11 | thrombotic disease | KG + DL |
| 12 | female breast carcinoma | KG + DL |
| 13 | primary cutaneous T-cell lymphoma | KG + DL |
| 14 | infectious bovine rhinotracheitis | KG + DL |
| 15 | malignant catarrh | KG + DL |
| 16 | cytomegalovirus infection | KG + DL |
| 17 | progesterone-receptor negative breast cancer | KG + DL |
| 18 | progesterone-receptor positive breast cancer | KG + DL |
| 19 | normal breast-like subtype of breast carcinoma | KG + DL |
| 20 | breast tumor luminal A or B | KG + DL |
| 21 | urinary bladder cancer | KG + DL |
| 22 | ureteric orifice cancer | KG + DL |
| 23 | urinary system neoplasm | KG + DL |
| 24 | heart neoplasm | KG + DL |
| 25 | multiple endocrine neoplasia | KG + DL |
| 26 | acute lymphoblastic leukemia (disease) | KG + DL |
| 27 | mycotic corneal ulcer | KG + DL |
| 28 | pulmonary hypertension | KG + DL |
| 29 | vein disease | KG + DL |
| 30 | hyperthyroidism | KG + DL |
| 31 | heart conduction disease | KG + DL |
| 32 | kyphoscoliotic heart disease | KG + DL |
| 33 | neuroblastoma | KG + DL |
| 34 | colonic neoplasm | KG + DL |
| 35 | ganglioneuroblastoma (disease) | KG + DL |
| 36 | drug-induced osteoporosis | KG + DL |
| 37 | cardiovascular disease | KG + DL |
| 38 | vertebral anomalies and variable endocrine and T-cell dysfunction | KG + DL |
| 39 | retroperitoneal neoplasm | KG + DL |
| 40 | heart valve disease | KG + DL |
| 41 | resistance to thyroid hormone due to a mutation in thyroid hormone receptor beta | KG + DL |
| 42 | congenital anomaly of ventricular septum | KG + DL |
| 43 | primary release disorder of platelets | KG + DL |
| 44 | Ewing sarcoma | KG + DL |
| 45 | Jeune syndrome situs inversus | KG + DL |
| 46 | Laubry-Pezzi syndrome | KG + DL |
| 47 | urinary bladder neoplasm | KG + DL |
| 48 | interventricular septum aneurysm | KG + DL |
| 49 | radioulnar synostosis with amegakaryocytic thrombocytopenia | KG + DL |
| 50 | heart disease | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.