Safinamide

Basic Information

Item Value
DrugBank ID DB06654
Evidence Level L5 (Computational Prediction)
Number of Predicted Indications 43

Predicted Indications (TxGNN)

The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.

# Indication Source
1 Rasmussen subacute encephalitis KG + DL
2 myelitis KG + DL
3 PLA2G6-associated neurodegeneration KG + DL
4 transaldolase deficiency KG + DL
5 fructose-1,6-bisphosphatase deficiency KG + DL
6 paralysis agitans, juvenile, of Hunt KG + DL
7 Lewy body dementia KG + DL
8 X-linked intellectual disability-ataxia-apraxia syndrome KG + DL
9 lethal infantile mitochondrial myopathy KG + DL
10 X-linked intellectual disability-cerebellar hypoplasia syndrome KG + DL
11 CLCN4-related X-linked intellectual disability syndrome KG + DL
12 hydrocephaly-cerebellar agenesis syndrome KG + DL
13 progressive supranuclear palsy-corticobasal syndrome KG + DL
14 X-linked intellectual disability-spastic quadriparesis syndrome KG + DL
15 X-linked spasticity-intellectual disability-epilepsy syndrome KG + DL
16 intellectual disability, X-linked, syndromic KG + DL
17 syndromic X-linked intellectual disability Chudley-Schwartz type KG + DL
18 Paganini-Miozzo syndrome KG + DL
19 X-linked cerebral-cerebellar-coloboma syndrome syndrome KG + DL
20 X-linked intellectual disability-hypotonia-movement disorder syndrome KG + DL
21 X-linked intellectual disability, Stocco dos Santos type KG + DL
22 polymicrogyria, perisylvian, with cerebellar hypoplasia and arthrogryposis KG + DL
23 Prieto syndrome KG + DL
24 intellectual developmental disorder, X-linked, syndromic, Hackmann-Di Donato type KG + DL
25 Basilicata-Akhtar syndrome KG + DL
26 NAA10-related syndrome KG + DL
27 MED12-related intellectual disability syndrome KG + DL
28 X-linked intellectual disability with hypopituitarism KG + DL
29 lissencephaly type 1 due to doublecortin gene mutation KG + DL
30 X-linked intellectual disability-craniofacioskeletal syndrome KG + DL
31 X-linked intellectual disability-precocious puberty-obesity syndrome KG + DL
32 holoprosencephaly 13, X-linked KG + DL
33 X-linked intellectual disability-acromegaly-hyperactivity syndrome KG + DL
34 atypical glycine encephalopathy KG + DL
35 Charcot-Marie-Tooth disease, demyelinating, type 1G KG + DL
36 congenital disorder of glycosylation with defective fucosylation KG + DL
37 retinal dystrophy with or without extraocular anomalies KG + DL
38 myopia X-linked KG + DL
39 myopia 26, X-linked, female-limited KG + DL
40 syndromic myopia KG + DL
41 hydranencephaly (disease) KG + DL
42 Gaucher disease-ophthalmoplegia-cardiovascular calcification syndrome KG + DL
43 schizophrenia KG + DL

Disclaimer

These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.


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