Pralatrexate
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB06813 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | pleural adenomatoid tumor | KG + DL |
| 2 | relapsing-remitting multiple sclerosis | KG + DL |
| 3 | pleural biphasic mesothelioma | KG + DL |
| 4 | pleural epithelioid mesothelioma | KG + DL |
| 5 | lymphohistiocytoid mesothelioma | KG + DL |
| 6 | pericardium cancer | KG + DL |
| 7 | pleural sarcomatoid mesothelioma | KG + DL |
| 8 | malignant peritoneal mesothelioma | KG + DL |
| 9 | well differentiated papillary mesothelioma | KG + DL |
| 10 | pleural mesothelioma | KG + DL |
| 11 | dermatofibrosarcoma protuberans | KG + DL |
| 12 | rhabdomyosarcoma (disease) | KG + DL |
| 13 | disorder of phenylalanine metabolism | KG + DL |
| 14 | botryoid-type embryonal rhabdomyosarcoma of the vagina | KG + DL |
| 15 | parameningeal embryonal rhabdomyosarcoma | KG + DL |
| 16 | iminoglycinuria | KG + DL |
| 17 | extrahepatic bile duct rhabdomyosarcoma | KG + DL |
| 18 | prostate embryonal rhabdomyosarcoma | KG + DL |
| 19 | embryonal extrahepatic bile duct rhabdomyosarcoma | KG + DL |
| 20 | malignant mesothelioma (disease) | KG + DL |
| 21 | disorder of tyrosine metabolism | KG + DL |
| 22 | acquired neutropenia | KG + DL |
| 23 | teratogenic Pierre Robin syndrome | KG + DL |
| 24 | liver sarcoma | KG + DL |
| 25 | EBV-positive T-cell lymphoproliferative disorder of childhood | KG + DL |
| 26 | ALK-negative anaplastic large cell lymphoma | KG + DL |
| 27 | chronic hepatitis B virus infection | KG + DL |
| 28 | fetal methylmercury syndrome | KG + DL |
| 29 | fibroblastic neoplasm | KG + DL |
| 30 | benign PEComa | KG + DL |
| 31 | uterine corpus perivascular epithelioid cell tumor | KG + DL |
| 32 | lymphangiomyoma | KG + DL |
| 33 | tetrahydrobiopterin-responsive hyperphenylalaninemia/phenylketonuria | KG + DL |
| 34 | conventional fibrosarcoma | KG + DL |
| 35 | heart fibrosarcoma | KG + DL |
| 36 | kidney fibrosarcoma | KG + DL |
| 37 | HIV infectious disease | KG + DL |
| 38 | low grade fibromyxoid sarcoma | KG + DL |
| 39 | chronic hepatitis C virus infection | KG + DL |
| 40 | angioimmunoblastic T-cell lymphoma | KG + DL |
| 41 | dermo-odonto dysplasia | KG + DL |
| 42 | lymphangioleiomyomatosis | KG + DL |
| 43 | pyelonephritis | KG + DL |
| 44 | obsolete teratozoospermia | KG + DL |
| 45 | multicentric osteolysis-nodulosis-arthropathy spectrum | KG + DL |
| 46 | ectrodactyly, ectodermal dysplasia, and cleft lip-palate syndrome | KG + DL |
| 47 | hypohidrotic ectodermal dysplasia-hypothyroidism-ciliary dyskinesia syndrome | KG + DL |
| 48 | hypoproteinemia, hypercatabolic | KG + DL |
| 49 | Naegeli-Franceschetti-Jadassohn syndrome | KG + DL |
| 50 | male infertility with teratozoospermia due to single gene mutation | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.