Lomitapide
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB08827 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 82 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | marcothrombocytopenia with mitral valve insufficiency | KG + DL |
| 2 | hereditary thrombocytopenia with normal platelets | KG + DL |
| 3 | dense granule disease | KG + DL |
| 4 | transient neonatal thrombocytopenia | KG + DL |
| 5 | thrombocytopenia | KG + DL |
| 6 | primary release disorder of platelets | KG + DL |
| 7 | pseudo-von Willebrand disease | KG + DL |
| 8 | Glanzmann thrombasthenia | KG + DL |
| 9 | hyperlipoproteinemia | KG + DL |
| 10 | platelet storage pool deficiency | KG + DL |
| 11 | hyperlipidemia, familial combined, LPL related | KG + DL |
| 12 | primary hyperoxaluria | KG + DL |
| 13 | Scott syndrome | KG + DL |
| 14 | obsolete familial combined hyperlipidemia | KG + DL |
| 15 | fibroma of prostate | KG + DL |
| 16 | fetal and neonatal alloimmune thrombocytopenia | KG + DL |
| 17 | cholesterol-ester transfer protein deficiency | KG + DL |
| 18 | benign reproductive system neoplasm | KG + DL |
| 19 | prostate cancer/brain cancer susceptibility | KG + DL |
| 20 | benign prostate phyllodes tumor | KG + DL |
| 21 | Brenner tumor | KG + DL |
| 22 | bleeding diathesis due to a collagen receptor defect | KG + DL |
| 23 | hemorrhagic disorder due to a constitutional thrombocytopenia | KG + DL |
| 24 | sitosterolemia | KG + DL |
| 25 | glaucoma | KG + DL |
| 26 | familial hypercholesterolemia | KG + DL |
| 27 | hypercholesterolemia, autosomal dominant | KG + DL |
| 28 | male reproductive organ cancer | KG + DL |
| 29 | hypercholesterolemia due to cholesterol 7alpha-hydroxylase deficiency | KG + DL |
| 30 | HIV infectious disease | KG + DL |
| 31 | neurodevelopmental disorder with ataxic gait, absent speech, and decreased cortical white matter | KG + DL |
| 32 | TAFRO syndrome | KG + DL |
| 33 | familial apolipoprotein C-II deficiency | KG + DL |
| 34 | prostate leiomyoma | KG + DL |
| 35 | thrombotic thrombocytopenic purpura | KG + DL |
| 36 | hyperlipidemia due to hepatic triglyceride lipase deficiency | KG + DL |
| 37 | platelet-type bleeding disorder | KG + DL |
| 38 | simian immunodeficiency virus infection | KG + DL |
| 39 | feline acquired immunodeficiency syndrome | KG + DL |
| 40 | hypertriglyceridemia, familial | KG + DL |
| 41 | cyclic hematopoiesis | KG + DL |
| 42 | major hypertriglyceridemia | KG + DL |
| 43 | inherited thrombophilia | KG + DL |
| 44 | arteriosclerosis disorder | KG + DL |
| 45 | hypolipoproteinemia (disease) | KG + DL |
| 46 | X-linked severe congenital neutropenia | KG + DL |
| 47 | Ehlers-Danlos syndrome, fibronectinemic type | KG + DL |
| 48 | lipase deficiency, combined | KG + DL |
| 49 | adult idiopathic neutropenia | KG + DL |
| 50 | familial chylomicronemia syndrome | KG + DL |
(Showing top 50 of 82 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.