Trametinib
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB08911 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 34 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | choroideremia | KG + DL |
| 2 | non-cutaneous melanoma | KG + DL |
| 3 | epithelioid cell melanoma | KG + DL |
| 4 | eyelid melanoma | KG + DL |
| 5 | scrotum melanoma | KG + DL |
| 6 | CDK4 linked melanoma | KG + DL |
| 7 | lentigo maligna melanoma | KG + DL |
| 8 | acral lentiginous melanoma (disease) | KG + DL |
| 9 | balloon cell malignant melanoma | KG + DL |
| 10 | superficial spreading melanoma | KG + DL |
| 11 | malignant melanoma of the mucosa | KG + DL |
| 12 | nodular malignant melanoma | KG + DL |
| 13 | amelanotic skin melanoma | KG + DL |
| 14 | choroidal dystrophy, central areolar | KG + DL |
| 15 | intestinal obstruction in the newborn due to guanylate cyclase 2C deficiency | KG + DL |
| 16 | bilateral parasagittal parieto-occipital polymicrogyria | KG + DL |
| 17 | amyotrophic lateral sclerosis | KG + DL |
| 18 | anus leiomyosarcoma | KG + DL |
| 19 | uterine corpus epithelioid leiomyosarcoma | KG + DL |
| 20 | uterine corpus myxoid leiomyosarcoma | KG + DL |
| 21 | borderline ovarian serous tumor | KG + DL |
| 22 | ovarian mucinous cystadenofibroma | KG + DL |
| 23 | retroperitoneal sarcoma | KG + DL |
| 24 | rete ovarii cystadenoma | KG + DL |
| 25 | small intestinal sarcoma | KG + DL |
| 26 | Mills syndrome | KG + DL |
| 27 | ovarian benign neoplasm | KG + DL |
| 28 | ovarian papillary cystadenoma | KG + DL |
| 29 | malignant ovarian Brenner tumor | KG + DL |
| 30 | serous neoplasm | KG + DL |
| 31 | mucinous ovarian cystadenoma | KG + DL |
| 32 | leiomyosarcoma | KG + DL |
| 33 | ovarian surface papilloma | KG + DL |
| 34 | amyotrophic lateral sclerosis, susceptibility to | KG + DL |
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.