Dabrafenib
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB08912 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 27 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | choroideremia | KG + DL |
| 2 | non-cutaneous melanoma | KG + DL |
| 3 | epithelioid cell melanoma | KG + DL |
| 4 | eyelid melanoma | KG + DL |
| 5 | scrotum melanoma | KG + DL |
| 6 | choroidal dystrophy, central areolar | KG + DL |
| 7 | amyotrophic lateral sclerosis | KG + DL |
| 8 | bilateral parasagittal parieto-occipital polymicrogyria | KG + DL |
| 9 | lentigo maligna melanoma | KG + DL |
| 10 | amelanotic skin melanoma | KG + DL |
| 11 | nodular malignant melanoma | KG + DL |
| 12 | malignant melanoma of the mucosa | KG + DL |
| 13 | superficial spreading melanoma | KG + DL |
| 14 | CDK4 linked melanoma | KG + DL |
| 15 | acral lentiginous melanoma (disease) | KG + DL |
| 16 | balloon cell malignant melanoma | KG + DL |
| 17 | axial spondylometaphyseal dysplasia | KG + DL |
| 18 | intestinal obstruction in the newborn due to guanylate cyclase 2C deficiency | KG + DL |
| 19 | Mills syndrome | KG + DL |
| 20 | amyotrophic lateral sclerosis, susceptibility to | KG + DL |
| 21 | lethal arthrogryposis-anterior horn cell disease syndrome | KG + DL |
| 22 | lower motor neuron syndrome with late-adult onset | KG + DL |
| 23 | trichomegaly-retina pigmentary degeneration-dwarfism syndrome | KG + DL |
| 24 | amyotrohpic lateral sclerosis type 22 | KG + DL |
| 25 | monomelic amyotrophy | KG + DL |
| 26 | autosomal dominant mitochondrial myopathy with exercise intolerance | KG + DL |
| 27 | poliomyelitis | KG + DL |
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.