Palbociclib
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB09073 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | hyperthyroidism | KG + DL |
| 2 | rheumatoid arthritis | KG + DL |
| 3 | thrombotic disease | KG + DL |
| 4 | resistance to thyroid hormone due to a mutation in thyroid hormone receptor beta | KG + DL |
| 5 | brachydactyly-syndactyly syndrome | KG + DL |
| 6 | myeloid leukemia | KG + DL |
| 7 | multiple endocrine neoplasia | KG + DL |
| 8 | colobomatous microphthalmia-rhizomelic dysplasia syndrome | KG + DL |
| 9 | hyperthyroxinemia | KG + DL |
| 10 | Prinzmetal angina | KG + DL |
| 11 | homozygous familial hypercholesterolemia | KG + DL |
| 12 | vein disease | KG + DL |
| 13 | thrombocytopenia | KG + DL |
| 14 | female breast carcinoma | KG + DL |
| 15 | Graves disease | KG + DL |
| 16 | marcothrombocytopenia with mitral valve insufficiency | KG + DL |
| 17 | hereditary thrombocytopenia with normal platelets | KG + DL |
| 18 | transient neonatal thrombocytopenia | KG + DL |
| 19 | plasma cell myeloma | KG + DL |
| 20 | dense granule disease | KG + DL |
| 21 | HIV infectious disease | KG + DL |
| 22 | cytomegalovirus infection | KG + DL |
| 23 | conjunctivitis | KG + DL |
| 24 | indolent plasma cell myeloma | KG + DL |
| 25 | non-inflammatory vasculopathy | KG + DL |
| 26 | malignant catarrh | KG + DL |
| 27 | infectious bovine rhinotracheitis | KG + DL |
| 28 | angiodysplasia | KG + DL |
| 29 | autosomal dominant familial hematuria-retinal arteriolar tortuosity-contractures syndrome | KG + DL |
| 30 | brain small vessel disease 1 with or without ocular anomalies | KG + DL |
| 31 | myelodysplastic syndrome | KG + DL |
| 32 | fibrocartilaginous embolism | KG + DL |
| 33 | venous thromboembolism | KG + DL |
| 34 | conjunctivitis (disease) | KG + DL |
| 35 | pulmonary hypertension | KG + DL |
| 36 | feline acquired immunodeficiency syndrome | KG + DL |
| 37 | simian immunodeficiency virus infection | KG + DL |
| 38 | partial deletion of the long arm of chromosome 5 | KG + DL |
| 39 | refractory cytopenia of childhood | KG + DL |
| 40 | unclassified myelodysplastic syndrome | KG + DL |
| 41 | neuroblastoma | KG + DL |
| 42 | diabetic nephropathy | KG + DL |
| 43 | congenital renal artery stenosis | KG + DL |
| 44 | kyphoscoliotic heart disease | KG + DL |
| 45 | aregenerative anemia | KG + DL |
| 46 | hemoglobinopathy | KG + DL |
| 47 | severe congenital hypochromic anemia with ringed sideroblasts | KG + DL |
| 48 | neonatal thyrotoxicosis | KG + DL |
| 49 | ganglioneuroblastoma (disease) | KG + DL |
| 50 | neurodevelopmental disorder with ataxic gait, absent speech, and decreased cortical white matter | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.