Nintedanib
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB09079 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | dermatofibrosarcoma protuberans | KG + DL |
| 2 | liposarcoma | KG + DL |
| 3 | ovarian myxoid liposarcoma | KG + DL |
| 4 | heart fibrosarcoma | KG + DL |
| 5 | axial spondylometaphyseal dysplasia | KG + DL |
| 6 | amyotrohpic lateral sclerosis type 22 | KG + DL |
| 7 | fibroblastic neoplasm | KG + DL |
| 8 | kidney fibrosarcoma | KG + DL |
| 9 | conventional fibrosarcoma | KG + DL |
| 10 | amyotrophic lateral sclerosis, susceptibility to | KG + DL |
| 11 | amyotrophic lateral sclerosis | KG + DL |
| 12 | bilateral parasagittal parieto-occipital polymicrogyria | KG + DL |
| 13 | low grade fibromyxoid sarcoma | KG + DL |
| 14 | trichomegaly-retina pigmentary degeneration-dwarfism syndrome | KG + DL |
| 15 | Mills syndrome | KG + DL |
| 16 | familial rhabdoid tumor | KG + DL |
| 17 | lower motor neuron syndrome with late-adult onset | KG + DL |
| 18 | extracutaneous mastocytoma | KG + DL |
| 19 | monomelic amyotrophy | KG + DL |
| 20 | autosomal dominant mitochondrial myopathy with exercise intolerance | KG + DL |
| 21 | lethal arthrogryposis-anterior horn cell disease syndrome | KG + DL |
| 22 | liver fibrosarcoma | KG + DL |
| 23 | cutaneous leiomyosarcoma (disease) | KG + DL |
| 24 | familial generalized lentiginosis | KG + DL |
| 25 | benign PEComa | KG + DL |
| 26 | rhabdoid tumor | KG + DL |
| 27 | uterine corpus perivascular epithelioid cell tumor | KG + DL |
| 28 | lymphangiomyoma | KG + DL |
| 29 | congenital multiple café-au-lait macules-increased sister chromatid exchange syndrome | KG + DL |
| 30 | acromelanosis | KG + DL |
| 31 | cutaneous undifferentiated pleomorphic sarcoma | KG + DL |
| 32 | gastrocutaneous syndrome | KG + DL |
| 33 | vulva sarcoma | KG + DL |
| 34 | leukonychia totalis-acanthosis-nigricans-like lesions-abnormal hair syndrome | KG + DL |
| 35 | central nervous system fibrosarcoma | KG + DL |
| 36 | lung PEComa | KG + DL |
| 37 | bone fibrosarcoma | KG + DL |
| 38 | peripheral nerve schwannoma | KG + DL |
| 39 | osteopathia striata-pigmentary dermopathy-white forelock syndrome | KG + DL |
| 40 | Moynahan syndrome | KG + DL |
| 41 | gallbladder leiomyosarcoma | KG + DL |
| 42 | breast fibrosarcoma | KG + DL |
| 43 | schwannoma of twelfth cranial nerve | KG + DL |
| 44 | sympathetic neurilemmoma | KG + DL |
| 45 | microcystic/reticular schwannoma | KG + DL |
| 46 | trigeminal schwannoma | KG + DL |
| 47 | severe combined immunodeficiency due to LAT deficiency | KG + DL |
| 48 | aggressive systemic mastocytosis | KG + DL |
| 49 | lymphangioleiomyomatosis | KG + DL |
| 50 | spindle cell liposarcoma | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.