Lumacaftor
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB09280 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | leprosy | KG + DL |
| 2 | migraine with or without aura, susceptibility to | KG + DL |
| 3 | migraine disorder | KG + DL |
| 4 | rheumatoid arthritis | KG + DL |
| 5 | pulmonary hypertension | KG + DL |
| 6 | kyphoscoliotic heart disease | KG + DL |
| 7 | migraine with brainstem aura | KG + DL |
| 8 | multiple endocrine neoplasia | KG + DL |
| 9 | brachydactyly-syndactyly syndrome | KG + DL |
| 10 | nephrogenic syndrome of inappropriate antidiuresis | KG + DL |
| 11 | homozygous familial hypercholesterolemia | KG + DL |
| 12 | Prinzmetal angina | KG + DL |
| 13 | colobomatous microphthalmia-rhizomelic dysplasia syndrome | KG + DL |
| 14 | atrophoderma vermiculata | KG + DL |
| 15 | ulerythema ophryogenesis | KG + DL |
| 16 | amyotrophic lateral sclerosis | KG + DL |
| 17 | persistent Mullerian duct syndrome | KG + DL |
| 18 | coronary artery disease | KG + DL |
| 19 | pneumocystosis | KG + DL |
| 20 | hypoalphalipoproteinemia | KG + DL |
| 21 | amyotrohpic lateral sclerosis type 22 | KG + DL |
| 22 | Mills syndrome | KG + DL |
| 23 | amyotrophic lateral sclerosis, susceptibility to | KG + DL |
| 24 | cerebral infarction | KG + DL |
| 25 | arteriosclerosis disorder | KG + DL |
| 26 | thrombotic disease | KG + DL |
| 27 | axial spondylometaphyseal dysplasia | KG + DL |
| 28 | HIV infectious disease | KG + DL |
| 29 | bilateral parasagittal parieto-occipital polymicrogyria | KG + DL |
| 30 | pediatric systemic lupus erythematosus | KG + DL |
| 31 | cytomegalovirus infection | KG + DL |
| 32 | generalized atherosclerosis | KG + DL |
| 33 | cerebral atherosclerosis | KG + DL |
| 34 | lethal arthrogryposis-anterior horn cell disease syndrome | KG + DL |
| 35 | trichomegaly-retina pigmentary degeneration-dwarfism syndrome | KG + DL |
| 36 | stroke disorder | KG + DL |
| 37 | intracranial arteriosclerosis | KG + DL |
| 38 | anomalous left coronary artery from the pulmonary artery | KG + DL |
| 39 | monomelic amyotrophy | KG + DL |
| 40 | conjunctivitis | KG + DL |
| 41 | female breast carcinoma | KG + DL |
| 42 | vein disease | KG + DL |
| 43 | lower motor neuron syndrome with late-adult onset | KG + DL |
| 44 | cerebral arterial disease | KG + DL |
| 45 | coronary atherosclerosis | KG + DL |
| 46 | oral candidiasis | KG + DL |
| 47 | intermittent vascular claudication | KG + DL |
| 48 | antithrombin deficiency type 2 | KG + DL |
| 49 | Bacteroidaceae infectious disease | KG + DL |
| 50 | obsolete susceptibility to ischemic stroke | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.