Talazoparib
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB11760 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | HER2 positive breast carcinoma | KG + DL |
| 2 | HIV infectious disease | KG + DL |
| 3 | progesterone-receptor negative breast cancer | KG + DL |
| 4 | progesterone-receptor positive breast cancer | KG + DL |
| 5 | normal breast-like subtype of breast carcinoma | KG + DL |
| 6 | breast tumor luminal A or B | KG + DL |
| 7 | multiple endocrine neoplasia | KG + DL |
| 8 | primary release disorder of platelets | KG + DL |
| 9 | simian immunodeficiency virus infection | KG + DL |
| 10 | feline acquired immunodeficiency syndrome | KG + DL |
| 11 | breast fibrocystic disease | KG + DL |
| 12 | pseudo-von Willebrand disease | KG + DL |
| 13 | cytomegalovirus infection | KG + DL |
| 14 | neurodevelopmental disorder with ataxic gait, absent speech, and decreased cortical white matter | KG + DL |
| 15 | infectious bovine rhinotracheitis | KG + DL |
| 16 | malignant catarrh | KG + DL |
| 17 | Glanzmann thrombasthenia | KG + DL |
| 18 | female breast carcinoma | KG + DL |
| 19 | drug-induced osteoporosis | KG + DL |
| 20 | benign mammary dysplasia | KG + DL |
| 21 | amenorrhea (disease) | KG + DL |
| 22 | apocrine adenosis of breast | KG + DL |
| 23 | blunt duct adenosis of breast | KG + DL |
| 24 | breast adenosis | KG + DL |
| 25 | lactation disease | KG + DL |
| 26 | breast abscess | KG + DL |
| 27 | fat necrosis of breast | KG + DL |
| 28 | thrombotic disease | KG + DL |
| 29 | Brenner tumor | KG + DL |
| 30 | benign reproductive system neoplasm | KG + DL |
| 31 | fibroma of prostate | KG + DL |
| 32 | liposarcoma | KG + DL |
| 33 | benign prostate phyllodes tumor | KG + DL |
| 34 | male reproductive organ cancer | KG + DL |
| 35 | thrombocytopenia | KG + DL |
| 36 | gestational trophoblastic neoplasm | KG + DL |
| 37 | prostate leiomyoma | KG + DL |
| 38 | hereditary thrombocytopenia with normal platelets | KG + DL |
| 39 | marcothrombocytopenia with mitral valve insufficiency | KG + DL |
| 40 | mycotic corneal ulcer | KG + DL |
| 41 | prostate cancer/brain cancer susceptibility | KG + DL |
| 42 | malignant prostate phyllodes tumor | KG + DL |
| 43 | common wart | KG + DL |
| 44 | transient neonatal thrombocytopenia | KG + DL |
| 45 | ovarian myxoid liposarcoma | KG + DL |
| 46 | dense granule disease | KG + DL |
| 47 | gestational uterine corpus choriocarcinoma | KG + DL |
| 48 | Leydig cell hypoplasia due to LH resistance | KG + DL |
| 49 | bone Paget disease | KG + DL |
| 50 | prostate cancer | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.