Neratinib
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB11828 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 86 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | progesterone-receptor positive breast cancer | KG + DL |
| 2 | normal breast-like subtype of breast carcinoma | KG + DL |
| 3 | progesterone-receptor negative breast cancer | KG + DL |
| 4 | breast tumor luminal A or B | KG + DL |
| 5 | synovium cancer | KG + DL |
| 6 | tenosynovial giant cell tumor | KG + DL |
| 7 | malignant giant cell tumor | KG + DL |
| 8 | tenosynovial giant cell tumor, localized type | KG + DL |
| 9 | fibroblastic neoplasm | KG + DL |
| 10 | kidney fibrosarcoma | KG + DL |
| 11 | conventional fibrosarcoma | KG + DL |
| 12 | benign PEComa | KG + DL |
| 13 | lymphangiomyoma | KG + DL |
| 14 | heart fibrosarcoma | KG + DL |
| 15 | uterine corpus perivascular epithelioid cell tumor | KG + DL |
| 16 | low grade fibromyxoid sarcoma | KG + DL |
| 17 | dermatofibrosarcoma protuberans | KG + DL |
| 18 | cutaneous undifferentiated pleomorphic sarcoma | KG + DL |
| 19 | malignant tenosynovial giant cell tumor | KG + DL |
| 20 | giant cell tumor | KG + DL |
| 21 | tendon sheath lipoma | KG + DL |
| 22 | tenosynovial giant cell tumor, diffuse type | KG + DL |
| 23 | central nervous system fibrosarcoma | KG + DL |
| 24 | cutaneous leiomyosarcoma (disease) | KG + DL |
| 25 | gallbladder leiomyosarcoma | KG + DL |
| 26 | acquired hemophagocytic lymphohistiocytosis associated with malignant disease | KG + DL |
| 27 | hemophagocytic syndrome associated with an infection | KG + DL |
| 28 | breast fibrosarcoma | KG + DL |
| 29 | liver fibrosarcoma | KG + DL |
| 30 | amyotrohpic lateral sclerosis type 22 | KG + DL |
| 31 | multifocal choroiditis | KG + DL |
| 32 | cysticercosis | KG + DL |
| 33 | amyotrophic lateral sclerosis, susceptibility to | KG + DL |
| 34 | lung PEComa | KG + DL |
| 35 | amyotrophic lateral sclerosis | KG + DL |
| 36 | Mills syndrome | KG + DL |
| 37 | lymphangioleiomyomatosis | KG + DL |
| 38 | axial spondylometaphyseal dysplasia | KG + DL |
| 39 | coenurosis | KG + DL |
| 40 | chromhidrosis | KG + DL |
| 41 | benign neoplasm of tongue | KG + DL |
| 42 | cervical neuroblastoma | KG + DL |
| 43 | schwannoma of jugular foramen | KG + DL |
| 44 | benign neoplasm of buccal mucosa | KG + DL |
| 45 | benign neoplasm of hypopharynx | KG + DL |
| 46 | nasal cavity inverting papilloma | KG + DL |
| 47 | jugular foramen meningioma | KG + DL |
| 48 | epiglottis neoplasm | KG + DL |
| 49 | benign neoplasm of floor of mouth | KG + DL |
| 50 | neoplasm of major salivary gland | KG + DL |
(Showing top 50 of 86 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.