Avelumab
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB11945 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | human herpesvirus 8-related tumor | KG + DL |
| 2 | middle ear neuroendocrine tumor | KG + DL |
| 3 | malignant cutaneous granular cell skin tumor | KG + DL |
| 4 | ectomesenchymoma | KG + DL |
| 5 | adenosine deaminase deficiency | KG + DL |
| 6 | reticular dysgenesis | KG + DL |
| 7 | Immunoerythromyeloid hypoplasia | KG + DL |
| 8 | non-severe combined immunodeficiency | KG + DL |
| 9 | prostatic urethra urothelial carcinoma | KG + DL |
| 10 | kidney pelvis sarcomatoid transitional cell carcinoma | KG + DL |
| 11 | infiltrating bladder urothelial carcinoma sarcomatoid variant | KG + DL |
| 12 | renal pelvis papillary urothelial carcinoma | KG + DL |
| 13 | lung fibrosis-immunodeficiency-46,XX gonadal dysgenesis syndrome | KG + DL |
| 14 | severe combined immunodeficiency due to LCK deficiency | KG + DL |
| 15 | T-B+ severe combined immunodeficiency due to gamma chain deficiency | KG + DL |
| 16 | T-B+ severe combined immunodeficiency due to CD45 deficiency | KG + DL |
| 17 | severe combined immunodeficiency (disease) | KG + DL |
| 18 | combined immunodeficiency, X-linked | KG + DL |
| 19 | glottis verrucous carcinoma | KG + DL |
| 20 | severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positive | KG + DL |
| 21 | supraglottis verrucous carcinoma | KG + DL |
| 22 | pancytopenia due to IKZF1 mutations | KG + DL |
| 23 | liver neuroendocrine carcinoma | KG + DL |
| 24 | Omenn syndrome | KG + DL |
| 25 | combined immunodeficiency due to CRAC channel dysfunction | KG + DL |
| 26 | purine nucleoside phosphorylase deficiency | KG + DL |
| 27 | absent thumb-short stature-immunodeficiency syndrome | KG + DL |
| 28 | facial dysmorphism-immunodeficiency-livedo-short stature syndrome | KG + DL |
| 29 | immuno-osseous dysplasia | KG + DL |
| 30 | primary immunodeficiency due to a defect in adaptive immunity | KG + DL |
| 31 | autoinflammatory syndrome with pyogenic bacterial infection and amylopectinosis | KG + DL |
| 32 | syndrome with combined immunodeficiency | KG + DL |
| 33 | hepatic veno-occlusive disease-immunodeficiency syndrome | KG + DL |
| 34 | transitional cell carcinoma | KG + DL |
| 35 | lipoma of the conjunctiva | KG + DL |
| 36 | pre-malignant neoplasm | KG + DL |
| 37 | cervical neuroblastoma | KG + DL |
| 38 | schwannoma of jugular foramen | KG + DL |
| 39 | benign neoplasm of buccal mucosa | KG + DL |
| 40 | nasopharyngeal teratoma | KG + DL |
| 41 | odontogenic cyst | KG + DL |
| 42 | benign neoplasm of tongue | KG + DL |
| 43 | inner ear neoplasm | KG + DL |
| 44 | epiglottis neoplasm | KG + DL |
| 45 | benign neoplasm of hypopharynx | KG + DL |
| 46 | combined immunodeficiency due to ORAI1 deficiency | KG + DL |
| 47 | benign neoplasm of floor of mouth | KG + DL |
| 48 | jugular foramen meningioma | KG + DL |
| 49 | cystic neoplasm | KG + DL |
| 50 | thyroglossal duct cyst | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.