Siponimod
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB12371 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | pulmonary hypertension | KG + DL |
| 2 | migraine disorder | KG + DL |
| 3 | kyphoscoliotic heart disease | KG + DL |
| 4 | migraine with brainstem aura | KG + DL |
| 5 | migraine with or without aura, susceptibility to | KG + DL |
| 6 | Prinzmetal angina | KG + DL |
| 7 | rheumatoid arthritis | KG + DL |
| 8 | atrophoderma vermiculata | KG + DL |
| 9 | ulerythema ophryogenesis | KG + DL |
| 10 | myelodysplastic syndrome | KG + DL |
| 11 | neuroblastoma | KG + DL |
| 12 | pulmonary hypertension, primary, autosomal recessive | KG + DL |
| 13 | brachydactyly-syndactyly syndrome | KG + DL |
| 14 | female breast carcinoma | KG + DL |
| 15 | leprosy | KG + DL |
| 16 | partial deletion of the long arm of chromosome 5 | KG + DL |
| 17 | colobomatous microphthalmia-rhizomelic dysplasia syndrome | KG + DL |
| 18 | refractory cytopenia of childhood | KG + DL |
| 19 | unclassified myelodysplastic syndrome | KG + DL |
| 20 | idiopathic pulmonary arterial hypertension | KG + DL |
| 21 | aregenerative anemia | KG + DL |
| 22 | severe congenital hypochromic anemia with ringed sideroblasts | KG + DL |
| 23 | ganglioneuroblastoma (disease) | KG + DL |
| 24 | obsolete patella aplasia, coxa vara, and tarsal synostosis | KG + DL |
| 25 | cor pulmonale | KG + DL |
| 26 | hyperthyroidism | KG + DL |
| 27 | retroperitoneal neoplasm | KG + DL |
| 28 | pulmonary hypertension, primary | KG + DL |
| 29 | coxopodopatellar syndrome | KG + DL |
| 30 | vertebral anomalies and variable endocrine and T-cell dysfunction | KG + DL |
| 31 | chromosome 17q23.1-q23.2 deletion syndrome | KG + DL |
| 32 | familial clubfoot due to 17q23.1q23.2 microduplication | KG + DL |
| 33 | allergic asthma | KG + DL |
| 34 | genetic multiple congenital anomalies/dysmorphic syndrome without intellectual disability | KG + DL |
| 35 | hypertrichosis (disease) | KG + DL |
| 36 | idiopathic and/or familial pulmonary arterial hypertension | KG + DL |
| 37 | gout | KG + DL |
| 38 | intrinsic asthma | KG + DL |
| 39 | nephrogenic syndrome of inappropriate antidiuresis | KG + DL |
| 40 | collagenopathy | KG + DL |
| 41 | lymphocytic hypereosinophilic syndrome | KG + DL |
| 42 | uterine polyp | KG + DL |
| 43 | gastrointestinal hamartoma | KG + DL |
| 44 | resistance to thyroid hormone due to a mutation in thyroid hormone receptor beta | KG + DL |
| 45 | polyp of vocal cord | KG + DL |
| 46 | polyp of middle ear | KG + DL |
| 47 | heritable pulmonary arterial hypertension | KG + DL |
| 48 | epulis | KG + DL |
| 49 | intermittent vascular claudication | KG + DL |
| 50 | fibroepithelial polyp | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.