Lurbinectedin
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB12674 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | multiple endocrine neoplasia | KG + DL |
| 2 | HIV infectious disease | KG + DL |
| 3 | rheumatoid arthritis | KG + DL |
| 4 | amyotrophic lateral sclerosis | KG + DL |
| 5 | cytomegalovirus infection | KG + DL |
| 6 | simian immunodeficiency virus infection | KG + DL |
| 7 | feline acquired immunodeficiency syndrome | KG + DL |
| 8 | malignant catarrh | KG + DL |
| 9 | infectious bovine rhinotracheitis | KG + DL |
| 10 | Mills syndrome | KG + DL |
| 11 | amyotrophic lateral sclerosis, susceptibility to | KG + DL |
| 12 | amyotrohpic lateral sclerosis type 22 | KG + DL |
| 13 | axial spondylometaphyseal dysplasia | KG + DL |
| 14 | neurodevelopmental disorder with ataxic gait, absent speech, and decreased cortical white matter | KG + DL |
| 15 | homozygous familial hypercholesterolemia | KG + DL |
| 16 | trichomegaly-retina pigmentary degeneration-dwarfism syndrome | KG + DL |
| 17 | bilateral parasagittal parieto-occipital polymicrogyria | KG + DL |
| 18 | lethal arthrogryposis-anterior horn cell disease syndrome | KG + DL |
| 19 | brachydactyly-syndactyly syndrome | KG + DL |
| 20 | lower motor neuron syndrome with late-adult onset | KG + DL |
| 21 | monomelic amyotrophy | KG + DL |
| 22 | colobomatous microphthalmia-rhizomelic dysplasia syndrome | KG + DL |
| 23 | autosomal dominant mitochondrial myopathy with exercise intolerance | KG + DL |
| 24 | thrombotic disease | KG + DL |
| 25 | antithrombin deficiency type 2 | KG + DL |
| 26 | heparin cofactor 2 deficiency | KG + DL |
| 27 | hypoalphalipoproteinemia | KG + DL |
| 28 | factor 5 excess with spontaneous thrombosis | KG + DL |
| 29 | gastrin secretion abnormality | KG + DL |
| 30 | acne (disease) | KG + DL |
| 31 | pediatric systemic lupus erythematosus | KG + DL |
| 32 | hyperthyroidism | KG + DL |
| 33 | transient neonatal thrombocytopenia | KG + DL |
| 34 | thrombocytopenia | KG + DL |
| 35 | resistance to thyroid hormone due to a mutation in thyroid hormone receptor beta | KG + DL |
| 36 | marcothrombocytopenia with mitral valve insufficiency | KG + DL |
| 37 | hereditary thrombocytopenia with normal platelets | KG + DL |
| 38 | dense granule disease | KG + DL |
| 39 | roseolovirus infectious disease | KG + DL |
| 40 | thrombophilia | KG + DL |
| 41 | benign recurrent intrahepatic cholestasis | KG + DL |
| 42 | HER2 positive breast carcinoma | KG + DL |
| 43 | gout | KG + DL |
| 44 | amenorrhea (disease) | KG + DL |
| 45 | vein disease | KG + DL |
| 46 | conjunctivitis | KG + DL |
| 47 | cholestasis | KG + DL |
| 48 | hereditary neuroendocrine tumor of small intestine | KG + DL |
| 49 | duodenal obstruction | KG + DL |
| 50 | abnormality of glucagon secretion | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.