Ivosidenib

Basic Information

Item Value
DrugBank ID DB14568
Evidence Level L5 (Computational Prediction)
Number of Predicted Indications 64

Predicted Indications (TxGNN)

The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.

# Indication Source
1 bulbar polio KG + DL
2 acute myeloid leukemia and myelodysplastic syndromes related to alkylating agent KG + DL
3 acute myeloid leukemia and myelodysplastic syndromes related to radiation KG + DL
4 5q35 microduplication syndrome KG + DL
5 neuralgic amyotrophy KG + DL
6 amyotrophic neuralgia KG + DL
7 myelodysplastic/myeloproliferative disease KG + DL
8 acute panmyelosis with myelofibrosis KG + DL
9 bilineal acute myeloid leukemia KG + DL
10 familial thrombocytosis KG + DL
11 reactive thrombocytosis KG + DL
12 chronic myelogenous leukemia, BCR-ABL1 positive KG + DL
13 ganglioneuroblastoma (disease) KG + DL
14 vertebral anomalies and variable endocrine and T-cell dysfunction KG + DL
15 retroperitoneal neoplasm KG + DL
16 inverse Klippel-Trenaunay syndrome KG + DL
17 fibromatosis, gingival KG + DL
18 acute megakaryoblastic leukemia KG + DL
19 metastatic melanoma KG + DL
20 neuroblastoma KG + DL
21 thrombocythemia KG + DL
22 lung hilum carcinoma KG + DL
23 poliomyelitis KG + DL
24 salivary gland type cancer of the breast KG + DL
25 breast papillomatosis KG + DL
26 lung benign neoplasm KG + DL
27 hamartoma of lung KG + DL
28 benign neoplasm of male breast KG + DL
29 giant adenofibroma of the breast KG + DL
30 diabetic mastopathy KG + DL
31 non-cutaneous melanoma KG + DL
32 fibroma of lung KG + DL
33 infiltrating nipple syringomatous adenoma KG + DL
34 subareolar duct papillomatosis KG + DL
35 granular cell tumor KG + DL
36 breast lipoma KG + DL
37 inclusion body myopathy with early-onset Paget disease with or without frontotemporal dementia KG + DL
38 intraductal breast papillomatosis KG + DL
39 benign eccrine breast spiradenoma KG + DL
40 breast leiomyoma KG + DL
41 fibroepithelial neoplasm KG + DL
42 breast cyst KG + DL
43 eyelid melanoma KG + DL
44 epithelioid cell melanoma KG + DL
45 ovarioleukodystrophy KG + DL
46 non-proliferative fibrocystic change of the breast KG + DL
47 pulmonary sulcus neoplasm KG + DL
48 lung germ cell tumor KG + DL
49 breast myoepitheliosis KG + DL
50 scrotum melanoma KG + DL

(Showing top 50 of 64 predictions)

Disclaimer

These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.


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